You have full access to this open access article. A literature review of full-length original studies in two databases, PubMed and Scopus, was performed.
The search period included observational studies in humans published between April 21, and March 20, A total of 26 studies were included.
Regarding CCH management, surgical interventions may be effective in reducing CCH when medical treatments have no response. In addition, an ocular examination by slit lamp is necessary to distinguish both conditions. However, surgical treatment options seem to be more effective in the complete elimination of CCH. Tear substitutes, vectored thermal pulsation, microblepharoexfoliation, and fitting contact lenses with low coefficient of friction seem to reduce and prevent lid-parallel conjunctival folds.
High-frequency radiowave electrosurgery seems to be a promising treatment for the complete elimination of conjunctivochalasis, avoiding the postoperative complications of traditional surgical techniques. Subsequent studies have suggested that LIPCOF are influenced by mechanical forces in blinks, being considered as a possible marker of dry eye symptoms [ 1 , 4 , 5 ].
In a comparative study, Veres et al. In a recent study, Pult et al. The results showed that LIPCOF were more pronounced in patients with dry eye symptoms compared to those without dry eye symptoms, and that blinking frequency and amplitude were lower in patients with dry eye symptoms.
