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Official websites use. Share sensitive information only on official, secure websites. Pico 1 , B. Lapergue 2 , M. Ferrigno 3 , M. Chadenat 1 , F. Bourdain 2 , E. Meseguer 4 , M. Obadia 5 , C. Hirel 1 , D. Duong 1 , S. Deltour 6 , C. Rosso 6 , P. Aegerter 7 , A. Cattenoy 8 , D. Smadja 9 , H. Hosseini 10 , B. Guillon 11 , V. Wolff 12 , Y. Samson 6 , C. Cordonnier 3 and P. Amarenco 4.
Remote ischemic per-conditioning—causing transient limb ischemia to induce ischemic tolerance in other organs—reduces final infarct size in animal stroke models and seems to have a neuroprotective effect in patients with acute ischemic stroke. Patients have been randomized to lower limb remote ischemic per-conditioning or sham group.
Remote ischemic per-conditioning consists of four cycles of electronic tourniquet inflation 5 min and deflation 5 min to a thigh within 6 h of symptom onset. Randomization has been stratified on IV thrombolysis. Mechanical thrombectomy was allowed.
MRI was repeated 24 h after stroke onset. The design has been published in Int J Of Stroke. A total of patients have been randomized 97 in the experimental arm and in the sham arm. Mean age was Main results will be presented at the session. The ClinicalTrials. Price 1 , L. Shaw 1 , P. Dodd 2 , C. Exley 3 , D. Flynn 4 , R. Francis 1 , S. Islam 5 , M.
Javanbakht 3 , R. Lakey 6 , J. Lally 3 , G. McClelland 7 , P. McMeekin 8 , H. Rodgers 1 , H. Snooks 5 , L. Sutcliffe 1 , P. Tyrell 9 , L. Vale 3 , A. Watkins 5 and G. Ford Despite evidence that intravenous thrombolysis IVT is an effective treatment for selected acute ischaemic stroke patients, large variations in delivery exist between stroke services.